• Article  

      Anti-MAG associated cerebellar ataxia and response to rituximab 

      Zis, Panagiotis; Rao, Dasappaiah Ganesh; Hoggard, Nigel; Sarrigiannis, Ptolemaios Georgios; Hadjivassiliou, Marios (2018)
      BACKGROUND: Myelin-associated glycoprotein (MAG) is a glycoprotein specific to Schwann cells. Schwann cells produce myelin for nerve cells in the peripheral nervous system. MAG also plays a role in the central nervous ...
    • Article  

      Axillary motor nerve conduction study: Description of technique and provision of normative data 

      Zis, Panagiotis; Hadjivassiliou, Marios; Rao, Dasappaiah Ganesh (2018)
      Background Axillary nerve lesions can commonly occur secondary to trauma or brachial plexopathy. Our aim was to describe our technique of axillary nerve motor conduction studies and provide the respective normal values. ...
    • Article  

      Chronic idiopathic axonal polyneuropathy: Prevalence of pain and impact on quality of life 

      Zis, Panagiotis; Sarrigiannis, Ptolemaios G.; Rao, Dasappaiah G.; Hewamadduma, Channa; Hadjivassiliou, Marios (2019)
      BACKGROUND AND AIM: Chronic idiopathic axonal polyneuropathy (CIAP) is a term describing axonal neuropathies of insidious onset, with slow or no progression of the disease over at least 6 months and with no etiology being ...
    • Article  

      The cortical focus in childhood absence epilepsy 

      Sarrigiannis, Ptolemaios G.; Zhao, Yifan; He, Fei; Billings, Stephen A.; Baster, Kathleen; Rittey, Chris; Yianni, John; Zis, Panagiotis; Wei, Hualiang; Hadjivassiliou, Marios; Grünewald, Richard (2018)
      OBJECTIVE: To determine the origin and dynamic characteristics of the generalised hyper-synchronous spike and wave (SW) discharges in childhood absence epilepsy (CAE). METHODS: We applied nonlinear methods, the error ...
    • Article  

      Electrophysiological determinants of the clinical severity of axonal peripheral neuropathy 

      Zis, Panagiotis; Hadjivassiliou, Marios; Rao, Dasappaiah Ganesh; Sarrigiannis, Ptolemaios Georgios (2019)
      INTRODUCTION: Electrophysiological diagnosis of axonal peripheral neuropathy (PN) is based on the attenuated amplitudes of nerve conduction studies (NCS), or a reduced sural/radial amplitude ratio (SRAR). We aimed to ...
    • Article  

      Gluten neuropathy: prevalence of neuropathic pain and the role of gluten-free diet 

      Zis, Panagiotis; Sarrigiannis, Ptolemaios Georgios; Rao, Dasappaiah Ganesh; Hadjivassiliou, Marios (2018)
      Peripheral neuropathy is a common extraintestinal manifestation of gluten sensitivity (gluten neuropathy). We aimed to establish the prevalence of neuropathic pain in patients with otherwise idiopathic PN and gluten ...
    • Article  

      Gluten Neuropathy: Prevalence of Pain and the Role of Gluten-Free Diet. (P2.091) 

      Zis, Panagiotis; Rao, Dasappaiah Ganesh; Sarrigiannis, Ptolemaios Georgios; Hadjivassiliou, Marios (2018)
      Objective: To establish the prevalence of pain in patients with gluten neuropathy (GN) and to describe any contributory factors.Background: Gluten neuropathy is the second commonest neurological manifestation of gluten ...
    • Article  

      Gluten sensitivity and epilepsy: a systematic review 

      Julian, Thomas; Hadjivassiliou, Marios; Zis, Panagiotis (2019)
      The aim of this systematic review was to establish the prevalence of epilepsy in patients with coeliac disease (CD) or gluten sensitivity (GS) and vice versa and to characterise the phenomenology of the epileptic syndromes ...
    • Article  

      Headache Associated with Coeliac Disease: A Systematic Review and Meta-Analysis 

      Zis, Panagiotis; Julian, Thomas; Hadjivassiliou, Marios (2018)
      OBJECTIVE: The aim of this systematic review was to explore the relationship between coeliac disease (CD) and headache. The objectives were to establish the prevalence of each entity amongst the other, to explore the role ...
    • Article  

      Increased Oxidative Stress as a Risk Factor in Chronic Idiopathic Axonal Polyneuropathy 

      Zis, Panagiotis; McHugh, Patrick C.; Manca, Maurizio; Sarrigiannis, Ptolemaios Georgios; Rao, Dasappaiah Ganesh; Hadjivassiliou, Marios (2018)
      Chronic idiopathic axonal polyneuropathy (CIAP) is a disorder with insidious onset and slow progression, where no etiology is identified despite appropriate investigations. We aimed to investigate the role of oxidative ...
    • Article  

      Movement Disorders Related to Gluten Sensitivity: A Systematic Review 

      Vinagre-Aragón, Ana; Zis, Panagiotis; Grunewald, Richard Adam; Hadjivassiliou, Marios (2018)
      Gluten related disorders (GRD) represent a wide spectrum of clinical manifestations that are triggered by the ingestion of gluten. Coeliac disease (CD) or gluten sensitive enteropathy is the most widely recognised, but ...
    • Article  

      Neurologic Deficits in Patients With Newly Diagnosed Celiac Disease Are Frequent and Linked With Autoimmunity to Transglutaminase 6 

      Hadjivassiliou, Marios; Croall, Iain D.; Zis, Panagiotis; Sarrigiannis, Ptolemaios G.; Sanders, David S.; Aeschlimann, Pascale; Grünewald, Richard A.; Armitage, Paul A.; Connolly, Daniel; Aeschlimann, Daniel; Hoggard, Nigel (2019)
      BACKGROUND & AIMS: Celiac disease is an autoimmune disorder induced by ingestion of gluten that affects 1% of the population and is characterized by gastrointestinal symptoms, weight loss, and anemia. We evaluated the ...
    • Book Chapter  

      Neurological manifestations of gluten sensitivity 

      Hadjivassiliou, Marios; Zis, Panagiotis (Springer International Publishing, 2019)
      This detailed, practical textbook focuses on immune mediated disorders of the nervous system with particular focus on systemic autoimmune disorders. Divided into three sections, the first discusses the neuroanatomical and ...
    • Article  

      Nocebo in cerebellar ataxia: A systematic review and meta-analysis of placebo-controlled clinical trials 

      Alam, Jawwaria M.; Hadjivassiliou, Marios; Zis, Panagiotis (2019)
      INTRODUCTION: Nocebo, the negative counterpart of the placebo phenomenon results in the induction of adverse events (AEs) following the administration of an inert substance. Nocebo has been demonstrated to be associated ...
    • Article  

      Nocebo in chronic inflammatory demyelinating polyneuropathy 

      Zis, Panagiotis; Hadjivassiliou, Marios; Sarrigiannis, Ptolemaios G.; Jenkins, Thomas M.; Mitsikostas, Dimos-Dimitrios (2018)
      INTRODUCTION: Nocebo is very prevalent among neurological disorders, resulting in low adherence and treatment outcome. We sought to examine the adverse events (AE) following placebo administration in placebo-controlled ...
    • Article  

      Novel genotype-phenotype and MRI correlations in a large cohort of patients with <i>SPG7</i> mutations 

      Hewamadduma, Channa A.; Hoggard, Nigel; O'Malley, Ronan; Robinson, Megan K.; Beauchamp, Nick J.; Segamogaite, Ruta; Martindale, Jo; Rodgers, Tobias; Rao, Ganesh; Sarrigiannis, Ptolemaios; Shanmugarajah, Priya; Zis, Panagiotis; Sharrack, Basil; McDermott, Christopher J.; Shaw, Pamela J.; Hadjivassiliou, Marios (2018)
      Objective To clinically, genetically, and radiologically characterize a large cohort of SPG7 patients. ...
    • Article  

      Pain in Chronic Inflammatory Demyelinating Polyradiculoneuropathy: A Systematic Review and Meta-Analysis 

      Michaelides, Athena; Hadden, Robert D. M.; Sarrigiannis, Ptolemaios G.; Hadjivassiliou, Marios; Zis, Panagiotis (2019)
      INTRODUCTION: Although chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) predominantly affects large myelinated fibers, many patients have pain. The aim of this paper is to systematically review the current ...
    • Article  

      Peripheral neuropathic pain in idiopathic Parkinson's disease: Prevalence and impact on quality of life 

      Adewusi, Joy K.; Hadjivassiliou, Marios; Vinagre-Aragón, Ana; O'Connor, Karen Ruth; Khan, Aijaz; Grünewald, Richard Adam; Zis, Panagiotis (2018)
      BACKGROUND AND PURPOSE: Pain is a frequent and debilitating non-motor symptom of Idiopathic Parkinson's Disease (IPD). The present study investigated the prevalence of pain and specifically peripheral neuropathic pain (PNP) ...
    • Book Chapter  

      Postinfectious Immune-Mediated Neurological Diseases 

      Hadjivassiliou, Marios; Zis, Panagiotis (Springer International Publishing, 2019)
      Infection may trigger immune-mediated neurological dysfunction. In some specific examples, the pathogenesis has been clearly delineated, with a detrimental effect of the immune response to infection. This chapter will cover ...
    • Article  

      Quality of Life in Patients with Gluten Neuropathy: A Case-Controlled Study 

      Zis, Panagiotis; Sarrigiannis, Ptolemaios Georgios; Rao, Dasappaiah Ganesh; Hadjivassiliou, Marios (2018)
      Background: Gluten neuropathy (GN) is defined as an otherwise idiopathic peripheral neuropathy in the presence of serological evidence of gluten sensitivity (positive native gliadin antibodies and/or transglutaminase or ...